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Anise oil (intraperitoneal injection; 9 mg/ml), 30 min before PTZ injection (n = 8). Anise oil was dissolved in ethanol. The final concentration of ethanol was less than 0.1 . All solutions used in control periods contained the same concentration of ethanol.Histological studiesMethodsIn vivo studies Electroencephalogram (EEG) recordings and PTZ-injectionAdult male Wistar rats, weighing 250?00 g (n
Rs DNA damage repair, leading to the intracellular accumulation of endogenous DNA. This defective DNA clearance stimulates systemic autoimmunity by inducing TLRindependent IFN- production. TREX1 mutations in humans lead to Aicardi-GoutieresAuthor Manuscript Author Manuscript Author Manuscript Author ManuscriptJ Autoimmun. Author manuscript; available in PMC 2016 November 01.Ghodke-Puranik and Niew
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